Usp22 Overexpression Leads to Aberrant Signal Transduction of Cancer-Related Pathways but Is Not Sufficient to Drive Tumor Formation in Mice

SIMPLE SUMMARY: Increased levels of the Usp22 deubiquitinase have been observed in several types of human cancer, particularly highly aggressive, therapy-resistant tumors. However, the role of Usp22 overexpression in cancer etiology is not known. To address whether Usp22 overexpression is sufficient...

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Detalles Bibliográficos
Autores principales: Kuang, Xianghong, McAndrew, Michael J., Mustachio, Lisa Maria, Chen, Ying-Jiun C., Atanassov, Boyko S., Lin, Kevin, Lu, Yue, Shen, Jianjun, Salinger, Andrew, Macatee, Timothy, Dent, Sharon Y. R., Koutelou, Evangelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428332/
https://www.ncbi.nlm.nih.gov/pubmed/34503086
http://dx.doi.org/10.3390/cancers13174276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428332/
https://www.ncbi.nlm.nih.gov/pubmed/34503086
http://dx.doi.org/10.3390/cancers13174276

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