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TP53 in Biology and Treatment of Osteosarcoma

SIMPLE SUMMARY: Treatment of osteosarcoma, apart from chemotherapy modifications, has not changed for approximately 30 years. Similarly, as in other tumors, mutations in the TP53 gene are often observed in osteosarcoma. In this article, we highlight the possibility of targeting p53 in the treatment...

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Detalles Bibliográficos
Autores principales: Synoradzki, Kamil Jozef, Bartnik, Ewa, Czarnecka, Anna M., Fiedorowicz, Michał, Firlej, Wiktoria, Brodziak, Anna, Stasinska, Agnieszka, Rutkowski, Piotr, Grieb, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428337/
https://www.ncbi.nlm.nih.gov/pubmed/34503094
http://dx.doi.org/10.3390/cancers13174284