Canonical NF-κB Promotes Lung Epithelial Cell Tumour Growth by Downregulating the Metastasis Suppressor CD82 and Enhancing Epithelial-to-Mesenchymal Cell Transition

SIMPLE SUMMARY: Canonical NF-κB signalling pathway acts as a tumour promoter in several types of cancer including non-small cell lung cancer (NSCLC), but the mechanism(s) by which it contributes to NSCLC is still under investigation. We show here that NF-κB RelA/p65 is required for the tumour growth...

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Detalles Bibliográficos
Autores principales: Roupakia, Eugenia, Chavdoula, Evangelia, Karpathiou, Georgia, Vatsellas, Giannis, Chatzopoulos, Dimitrios, Mela, Angeliki, Gillette, Jennifer M., Kriegsmann, Katharina, Kriegsmann, Mark, Batistatou, Anna, Goussia, Anna, Marcu, Kenneth B., Karteris, Emmanouil, Klinakis, Apostolos, Kolettas, Evangelos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428346/
https://www.ncbi.nlm.nih.gov/pubmed/34503110
http://dx.doi.org/10.3390/cancers13174302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428346/
https://www.ncbi.nlm.nih.gov/pubmed/34503110
http://dx.doi.org/10.3390/cancers13174302

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