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A Genome-Wide Profiling of Glioma Patients with an IDH1 Mutation Using the Catalogue of Somatic Mutations in Cancer Database

SIMPLE SUMMARY: Glioma patients that present a somatic mutation in the isocitrate dehydrogenase 1 (IDH1) gene have a significantly better prognosis and overall survival than patients with the wild-type genotype. An IDH1 mutation is hypothesized to occur early during cellular transformation and leads...

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Detalles Bibliográficos
Autores principales: Pappula, Amrit L., Rasheed, Shayaan, Mirzaei, Golrokh, Petreaca, Ruben C., Bouley, Renee A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428353/
https://www.ncbi.nlm.nih.gov/pubmed/34503108
http://dx.doi.org/10.3390/cancers13174299