Design, Synthesis and Biological Activity of C3 Hemisynthetic Triterpenic Esters as Novel Antitrypanosomal Hits

Research for innovative drugs is crucial to contribute to parasitic infections control and eradication. Inspired by natural antiprotozoal triterpenes, a library of 12 hemisynthetic 3‐O‐arylalkyl esters was derived from ursolic and oleanolic acids through one‐step synthesis. Compounds were tested on...

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Detalles Bibliográficos
Autores principales: Schioppa, Laura, Beaufay, Claire, Bonneau, Natacha, Sanchez, Marianela, Girardi, Cynthia, Leverrier, Aurélie, Ortiz, Sergio, Palermo, Jorge, Poupaert, Jacques H., Quetin‐Leclercq, Joëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428374/
https://www.ncbi.nlm.nih.gov/pubmed/34499412
http://dx.doi.org/10.1002/open.202100159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428374/
https://www.ncbi.nlm.nih.gov/pubmed/34499412
http://dx.doi.org/10.1002/open.202100159

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