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Structural Basis of Covalent Inhibitory Mechanism of TMPRSS2-Related Serine Proteases by Camostat

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen causing the coronavirus disease 2019 (COVID-19) global pandemic. No effective treatment for COVID-19 has been established yet. The serine protease transmembrane protease serine 2 (TMPRSS2) is essential for viral sprea...

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Detalles Bibliográficos
Autores principales: Sun, Gaohui, Sui, Yaqun, Zhou, Yang, Ya, Junlin, Yuan, Cai, Jiang, Longguang, Huang, Mingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428381/
https://www.ncbi.nlm.nih.gov/pubmed/34160253
http://dx.doi.org/10.1128/JVI.00861-21