Marburg and Ebola Virus mRNA 3′ Untranslated Regions Contain Negative Regulators of Translation That Are Modulated by ADAR1 Editing

The filovirus family includes deadly pathogens such as Ebola virus (EBOV) and Marburg virus (MARV). A substantial portion of filovirus genomes encode 5′ and 3′ untranslated regions (UTRs) of viral mRNAs. Select viral genomic RNA sequences corresponding to 3′ UTRs are prone to editing by adenosine de...

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Detalles Bibliográficos
Autores principales: Khadka, Sudip, Williams, Caroline G., Sweeney-Gibbons, Joyce, Basler, Christopher F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428382/
https://www.ncbi.nlm.nih.gov/pubmed/34346762
http://dx.doi.org/10.1128/JVI.00652-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428382/
https://www.ncbi.nlm.nih.gov/pubmed/34346762
http://dx.doi.org/10.1128/JVI.00652-21

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