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Engineered Promoter-Switched Viruses Reveal the Role of Poxvirus Maturation Protein A26 as a Negative Regulator of Viral Spread

Vaccinia virus produces two types of virions known as single-membraned intracellular mature virus (MV) and double-membraned extracellular enveloped virus (EV). EV production peaks earlier when initial MVs are further wrapped and secreted to spread infection within the host. However, late during infe...

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Detalles Bibliográficos
Autores principales: Holley, Joe, Sumner, Rebecca P., Lant, Sian, Ribeca, Paolo, Ulaeto, David, Maluquer de Motes, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428399/
https://www.ncbi.nlm.nih.gov/pubmed/34260287
http://dx.doi.org/10.1128/JVI.01012-21