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Engineered Promoter-Switched Viruses Reveal the Role of Poxvirus Maturation Protein A26 as a Negative Regulator of Viral Spread
Vaccinia virus produces two types of virions known as single-membraned intracellular mature virus (MV) and double-membraned extracellular enveloped virus (EV). EV production peaks earlier when initial MVs are further wrapped and secreted to spread infection within the host. However, late during infe...
Autores principales: | Holley, Joe, Sumner, Rebecca P., Lant, Sian, Ribeca, Paolo, Ulaeto, David, Maluquer de Motes, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428399/ https://www.ncbi.nlm.nih.gov/pubmed/34260287 http://dx.doi.org/10.1128/JVI.01012-21 |
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