Improved Genome Packaging Efficiency of Adeno-associated Virus Vectors Using Rep Hybrids

Recombinant adeno-associated viruses (rAAVs) are one of the most commonly used vectors for a variety of gene therapy applications. In the last 2 decades, research focused primarily on the characterization and isolation of new cap, genes resulting in hundreds of natural and engineered AAV capsid vari...

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Detalles Bibliográficos
Autores principales: Mietzsch, Mario, Eddington, Courtnee, Jose, Ariana, Hsi, Jane, Chipman, Paul, Henley, Tom, Choudhry, Modassir, McKenna, Robert, Agbandje-McKenna, Mavis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Structure and Assembly
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428402/
https://www.ncbi.nlm.nih.gov/pubmed/34287038
http://dx.doi.org/10.1128/JVI.00773-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428402/
https://www.ncbi.nlm.nih.gov/pubmed/34287038
http://dx.doi.org/10.1128/JVI.00773-21

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