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Plasma Membrane Ca(2+) Pump PMCA4z Is More Active Than Splicing Variant PMCA4x

The plasma membrane Ca(2+) pumps (PMCA) are P-ATPases that control Ca(2+) signaling and homeostasis by transporting Ca(2+) out of the eukaryotic cell. Humans have four genes that code for PMCA isoforms (PMCA1-4). A large diversity of PMCA isoforms is generated by alternative mRNA splicing at sites A...

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Detalles Bibliográficos
Autores principales: Corradi, Gerardo R., Mazzitelli, Luciana R., Petrovich, Guido D., de Tezanos Pinto, Felicitas, Rochi, Lucia, Adamo, Hugo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428515/
https://www.ncbi.nlm.nih.gov/pubmed/34512262
http://dx.doi.org/10.3389/fncel.2021.668371