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RhoC Modulates Cell Junctions and Type I Interferon Response in Aggressive Breast Cancers

Metastases are the leading cause of death in cancer patients. RhoC, a member of the Rho GTPase family, has been shown to facilitate metastasis of aggressive breast cancer cells by influencing motility, invasion, and chemokine secretion, but as yet there is no integrated model of the precise mechanis...

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Detalles Bibliográficos
Autores principales: Abraham, Hannah G., Ulintz, Peter J., Goo, Laura, Yates, Joel A., Little, Andrew C., Bao, Liwei, Wu, Zhifen, Merajver, Sofia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428533/
https://www.ncbi.nlm.nih.gov/pubmed/34513691
http://dx.doi.org/10.3389/fonc.2021.712041