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MixTwice: large-scale hypothesis testing for peptide arrays by variance mixing

SUMMARY: Peptide microarrays have emerged as a powerful technology in immunoproteomics as they provide a tool to measure the abundance of different antibodies in patient serum samples. The high dimensionality and small sample size of many experiments challenge conventional statistical approaches, in...

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Detalles Bibliográficos
Autores principales: Zheng, Zihao, Mergaert, Aisha M., Ong, Irene M., Shelef, Miriam A., Newton, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428605/
https://www.ncbi.nlm.nih.gov/pubmed/33693483
http://dx.doi.org/10.1093/bioinformatics/btab162