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MixTwice: large-scale hypothesis testing for peptide arrays by variance mixing
SUMMARY: Peptide microarrays have emerged as a powerful technology in immunoproteomics as they provide a tool to measure the abundance of different antibodies in patient serum samples. The high dimensionality and small sample size of many experiments challenge conventional statistical approaches, in...
Autores principales: | Zheng, Zihao, Mergaert, Aisha M., Ong, Irene M., Shelef, Miriam A., Newton, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428605/ https://www.ncbi.nlm.nih.gov/pubmed/33693483 http://dx.doi.org/10.1093/bioinformatics/btab162 |
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