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Infecting mosquitoes alters DENV-2 characteristics and enhances hemorrhage-induction potential in Stat1(-/-) mice

Dengue is one of the most prevalent arthropod-borne viral diseases in humans. There is still no effective vaccine or treatment to date. Previous studies showed that mosquito-derived factors present in saliva or salivary gland extract (SGE) contribute to the pathogenesis of dengue. In this study, we...

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Detalles Bibliográficos
Autores principales: Cheang, Ka Wan, Chen, Wen-Yu, Wu-Hsieh, Betty A., Shiao, Shin-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428656/
https://www.ncbi.nlm.nih.gov/pubmed/34449772
http://dx.doi.org/10.1371/journal.pntd.0009728