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Unconditioned and learned morphine tolerance influence hippocampal-dependent short-term memory and the subjacent expression of GABA-A receptor alpha subunits

BACKGROUND: ɣ-aminobutyric acid (GABA) facilitator valproic acid may be able to curb memory disruption induced by morphine exposure. OBJECTIVE: The effects of the GABA facilitator valproic acid on the behavioral tolerance induced by morphine were investigated. Then hippocampal-dependent tasks named...

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Detalles Bibliográficos
Autores principales: Ghamkharinejad, Ghazaleh, Marashi, Seyed Hossein, Foolad, Forough, Javan, Mohammad, Fathollahi, Yaghoub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428970/
https://www.ncbi.nlm.nih.gov/pubmed/34500453
http://dx.doi.org/10.1371/journal.pone.0253902