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Pre-existing T cell-mediated cross-reactivity to SARS-CoV-2 cannot solely be explained by prior exposure to endemic human coronaviruses

T-cell-mediated immunity to SARS-CoV-2-derived peptides in individuals unexposed to SARS-CoV-2 has been previously reported. This pre-existing immunity was suggested to largely derive from prior exposure to ‘common cold’ endemic human coronaviruses (HCoVs). To test this, we characterised the sequenc...

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Detalles Bibliográficos
Autores principales: Tan, Cedric C.S., Owen, Christopher J., Tham, Christine Y.L., Bertoletti, Antonio, van Dorp, Lucy, Balloux, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428999/
https://www.ncbi.nlm.nih.gov/pubmed/34509646
http://dx.doi.org/10.1016/j.meegid.2021.105075