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Integrative Network Analysis Revealed Genetic Impact of Pyruvate Kinase L/R on Hepatocyte Proliferation and Graft Survival after Liver Transplantation

BACKGROUND: Pyruvate kinase L/R (PKLR) has been suggested to affect the proliferation of hepatocytes via regulation of the cell cycle and lipid metabolism. However, its impact on the global metabolome and its clinical implications remain unclear. AIMS: We aimed to clarify the genetic impact of PKLR...

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Detalles Bibliográficos
Autores principales: Liu, Zhengtao, Zhao, Junsheng, Wang, Wenchao, Zhu, Hai, Qian, Junjie, Wang, Shuai, Que, Shuping, Zhang, Feng, Yin, Shengyong, Zhou, Lin, Geng, Lei, Zheng, Shusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429008/
https://www.ncbi.nlm.nih.gov/pubmed/34512869
http://dx.doi.org/10.1155/2021/7182914