Urine levels of the polyglutamine ataxin-3 protein are elevated in patients with spinocerebellar ataxia type 3

INTRODUCTION: Accumulation of polyglutamine (polyQ) ataxin-3 (ATXN3) contributes to the pathobiology of spinocerebellar ataxia type 3 (SCA3). Recently, we showed that polyQ ATXN3 is elevated in the plasma and cerebrospinal fluid (CSF) of SCA3 patients, and has the potential to serve as a biological...

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Detalles Bibliográficos
Autores principales: Koike, Yuka, Jansen-West, Karen R., AL-Shaikh, Rana Hanna, Carlomagno, Yari, Song, Yuping, Dunmore, Judith A., LeDoux, Mark S., Friedman, Joseph H., Pena, Ashley B., Uitti, Ryan J., Zaremba, Jacek, van Gerpen, Jay A., Pfeiffer, Ronald F., Veerappan, Venka, Aiba, Ikuko, Hashimoto, Rina, Giles, Samuel S., Shah, Jaimin S., Tipton, Philip W., Huang, Josephine F., Wierenga, Klaas J., Aasly, Jan, Fryer, John D., Petrucelli, Leonard, Wszolek, Zbigniew K., Prudencio, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429134/
https://www.ncbi.nlm.nih.gov/pubmed/34303201
http://dx.doi.org/10.1016/j.parkreldis.2021.07.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429134/
https://www.ncbi.nlm.nih.gov/pubmed/34303201
http://dx.doi.org/10.1016/j.parkreldis.2021.07.018

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