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Autophagy induced by H. pylori VacA regulated the survival mechanism of the SGC7901 human gastric cancer cell line

BACKGROUND: Vacuolating cytotoxin (VacA) is an important virulence factor of Helicobacter pylori (H. pylori). It was previously believed that VacA can trigger the cascade of apoptosis on mitochondria to lead to cell apoptosis. Recently, it was found that VacA can induce autophagy. However, the molec...

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Detalles Bibliográficos
Autores principales: Luo, Juan, Bai, Luyan, Tao, Jun, Wen, Yu, Li, Mingke, Zhu, Yunzhen, Luo, Sufeng, Pu, Guangyu, Ma, Lanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429402/
https://www.ncbi.nlm.nih.gov/pubmed/34398448
http://dx.doi.org/10.1007/s13258-021-01151-7