Chronic exposure to Cytolethal Distending Toxin (CDT) promotes a cGAS-dependent type I interferon response

The Cytolethal Distending Toxin (CDT) is a bacterial genotoxin produced by pathogenic bacteria causing major foodborne diseases worldwide. CDT activates the DNA Damage Response and modulates the host immune response, but the precise relationship between these outcomes has not been addressed so far....

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Detalles Bibliográficos
Autores principales: Pons, Benoît J., Pettes-Duler, Aurélie, Naylies, Claire, Taieb, Frédéric, Bouchenot, Catherine, Hashim, Saleha, Rouimi, Patrick, Deslande, Maxime, Lippi, Yannick, Mirey, Gladys, Vignard, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429409/
https://www.ncbi.nlm.nih.gov/pubmed/34308492
http://dx.doi.org/10.1007/s00018-021-03902-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429409/
https://www.ncbi.nlm.nih.gov/pubmed/34308492
http://dx.doi.org/10.1007/s00018-021-03902-x

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