Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling

Free L-tryptophan (L-Trp) stalls ribosomes engaged in the synthesis of TnaC, a leader peptide controlling the expression of the Escherichia coli tryptophanase operon. Despite extensive characterization, the molecular mechanism underlying the recognition and response to L-Trp by the TnaC-ribosome com...

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Detalles Bibliográficos
Autores principales: van der Stel, Anne-Xander, Gordon, Emily R., Sengupta, Arnab, Martínez, Allyson K., Klepacki, Dorota, Perry, Thomas N., Herrero del Valle, Alba, Vázquez-Laslop, Nora, Sachs, Matthew S., Cruz-Vera, Luis R., Innis, C. Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429421/
https://www.ncbi.nlm.nih.gov/pubmed/34504068
http://dx.doi.org/10.1038/s41467-021-25663-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429421/
https://www.ncbi.nlm.nih.gov/pubmed/34504068
http://dx.doi.org/10.1038/s41467-021-25663-8

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