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The tumor suppressor miR-642a-5p targets Wilms Tumor 1 gene and cell-cycle progression in prostate cancer

RNA-based therapeutics are emerging as innovative options for cancer treatment, with microRNAs being attractive targets for therapy development. We previously implicated microRNA-642a-5p (miR-642a-5p) as a tumor suppressor in prostate cancer (PCa), and here we characterize its mode of action, using...

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Detalles Bibliográficos
Autores principales: Beveridge, Dianne J., Richardson, Kirsty L., Epis, Michael R., Brown, Rikki A. M., Stuart, Lisa M., Woo, Andrew J., Leedman, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429423/
https://www.ncbi.nlm.nih.gov/pubmed/34504167
http://dx.doi.org/10.1038/s41598-021-97190-x