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Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease

Resting state functional connectivity (rs-fMRI) is impaired early in persons who subsequently develop Alzheimer’s disease (AD) dementia. This impairment may be leveraged to aid investigation of the pre-clinical phase of AD. We developed a model that predicts brain age from resting state (rs)-fMRI da...

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Detalles Bibliográficos
Autores principales: Gonneaud, Julie, Baria, Alex T., Pichet Binette, Alexa, Gordon, Brian A., Chhatwal, Jasmeer P., Cruchaga, Carlos, Jucker, Mathias, Levin, Johannes, Salloway, Stephen, Farlow, Martin, Gauthier, Serge, Benzinger, Tammie L. S., Morris, John C., Bateman, Randall J., Breitner, John C. S., Poirier, Judes, Vachon-Presseau, Etienne, Villeneuve, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429427/
https://www.ncbi.nlm.nih.gov/pubmed/34504080
http://dx.doi.org/10.1038/s41467-021-25492-9