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Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease
Resting state functional connectivity (rs-fMRI) is impaired early in persons who subsequently develop Alzheimer’s disease (AD) dementia. This impairment may be leveraged to aid investigation of the pre-clinical phase of AD. We developed a model that predicts brain age from resting state (rs)-fMRI da...
Autores principales: | Gonneaud, Julie, Baria, Alex T., Pichet Binette, Alexa, Gordon, Brian A., Chhatwal, Jasmeer P., Cruchaga, Carlos, Jucker, Mathias, Levin, Johannes, Salloway, Stephen, Farlow, Martin, Gauthier, Serge, Benzinger, Tammie L. S., Morris, John C., Bateman, Randall J., Breitner, John C. S., Poirier, Judes, Vachon-Presseau, Etienne, Villeneuve, Sylvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429427/ https://www.ncbi.nlm.nih.gov/pubmed/34504080 http://dx.doi.org/10.1038/s41467-021-25492-9 |
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