Oxidized mitochondrial DNA sensing by STING signaling promotes the antitumor effect of an irradiated immunogenic cancer cell vaccine

Exposure to ionizing radiation, a physical treatment that inactivates live tumor cells, has been extensively applied to enhance the antitumor responses induced by cancer cell vaccines in both animal research and human clinical trials. However, the mechanisms by which irradiated cells function as imm...

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Detalles Bibliográficos
Autores principales: Fang, Chunju, Mo, Fei, Liu, Li, Du, Jing, Luo, Min, Men, Ke, Na, Feifei, Wang, Wei, Yang, Hanshuo, Wei, Xiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429462/
https://www.ncbi.nlm.nih.gov/pubmed/32398808
http://dx.doi.org/10.1038/s41423-020-0456-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429462/
https://www.ncbi.nlm.nih.gov/pubmed/32398808
http://dx.doi.org/10.1038/s41423-020-0456-1

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