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Bone Mesenchymal Stem Cells Promote Extracellular Matrix Remodeling of Degenerated Nucleus Pulposus Cells via the miR-101-3p/EIF4G2 Axis

The etiology of lumbocrural pain is tightly concerned with intervertebral disk degeneration (IDD). Bone mesenchymal stem cell (BMSC)-based therapy bears potentials for IDD treatment. The properties of microRNA (miRNA)-modified BMSCs may be altered. This study investigated the role and mechanism of B...

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Detalles Bibliográficos
Autores principales: Wang, Zeng, Ding, Xiaolin, Cao, Feifei, Zhang, Xishan, Wu, Jingguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429483/
https://www.ncbi.nlm.nih.gov/pubmed/34513803
http://dx.doi.org/10.3389/fbioe.2021.642502