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Genomic landscape of gliosarcoma: distinguishing features and targetable alterations

Gliosarcoma is an aggressive brain tumor with histologic features of glioblastoma (GBM) and soft tissue sarcoma. Despite its poor prognosis, its rarity has precluded analysis of its underlying biology. We used a multi-center database to characterize the genomic landscape of gliosarcoma. Sequencing d...

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Detalles Bibliográficos
Autores principales: Zaki, Mark M., Mashouf, Leila A., Woodward, Eleanor, Langat, Pinky, Gupta, Saksham, Dunn, Ian F., Wen, Patrick Y., Nahed, Brian V., Bi, Wenya Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429571/
https://www.ncbi.nlm.nih.gov/pubmed/34504233
http://dx.doi.org/10.1038/s41598-021-97454-6