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Nano-hydroxyapatite accelerates vascular calcification via lysosome impairment and autophagy dysfunction in smooth muscle cells

Vascular calcification (VC) is a common characteristic of aging, diabetes, chronic renal failure, and atherosclerosis. The basic component of VC is hydroxyapatite (HAp). Nano-sized HAp (nHAp) has been identified to play an essential role in the development of pathological calcification of vasculatur...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Luo, Yi, Zhao, Yun, Xiang, Pingping, Zhu, Jinyun, Jing, Wangwei, Jin, Wenjing, Chen, Mingyao, Tang, Ruikang, Yu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429627/
https://www.ncbi.nlm.nih.gov/pubmed/34541414
http://dx.doi.org/10.1016/j.bioactmat.2021.06.004