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Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population

Whole-genome doubling (WGD) is an early macro-evolutionary event in tumorigenesis, involving the doubling of an entire chromosome complement. However, its impact on breast cancer subtypes remains unclear. Here, we performed a comprehensive and quantitative analysis of WGD and its influence on breast...

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Detalles Bibliográficos
Autores principales: Wu, Chia-Hsin, Hsieh, Chia-Shan, Chang, Yo-Cheng, Huang, Chi-Cheng, Yeh, Hsien-Tang, Hou, Ming-Feng, Chung, Yuan-Chiang, Tu, Shih-Hsin, Chang, King-Jen, Chattopadhyay, Amrita, Lai, Liang-Chuan, Lu, Tzu-Pin, Li, Yung-Hua, Tsai, Mong-Hsun, Chuang, Eric Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429690/
https://www.ncbi.nlm.nih.gov/pubmed/34504292
http://dx.doi.org/10.1038/s42003-021-02597-x