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Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population
Whole-genome doubling (WGD) is an early macro-evolutionary event in tumorigenesis, involving the doubling of an entire chromosome complement. However, its impact on breast cancer subtypes remains unclear. Here, we performed a comprehensive and quantitative analysis of WGD and its influence on breast...
Autores principales: | Wu, Chia-Hsin, Hsieh, Chia-Shan, Chang, Yo-Cheng, Huang, Chi-Cheng, Yeh, Hsien-Tang, Hou, Ming-Feng, Chung, Yuan-Chiang, Tu, Shih-Hsin, Chang, King-Jen, Chattopadhyay, Amrita, Lai, Liang-Chuan, Lu, Tzu-Pin, Li, Yung-Hua, Tsai, Mong-Hsun, Chuang, Eric Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429690/ https://www.ncbi.nlm.nih.gov/pubmed/34504292 http://dx.doi.org/10.1038/s42003-021-02597-x |
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