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Boosting and lassoing new prostate cancer SNP risk factors and their connection to selenium

We begin by arguing that the often used algorithm for the discovery and use of disease risk factors, stepwise logistic regression, is unstable. We then argue that there are other algorithms available that are much more stable and reliable (e.g. the lasso and gradient boosting). We then propose a pro...

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Detalles Bibliográficos
Autores principales: Booth, David E., Gopalakrishna-Remani, Venugopal, Cooper, Matthew L., Green, Fiona R., Rayman, Margaret P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429712/
https://www.ncbi.nlm.nih.gov/pubmed/34504230
http://dx.doi.org/10.1038/s41598-021-97412-2