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Boosting and lassoing new prostate cancer SNP risk factors and their connection to selenium
We begin by arguing that the often used algorithm for the discovery and use of disease risk factors, stepwise logistic regression, is unstable. We then argue that there are other algorithms available that are much more stable and reliable (e.g. the lasso and gradient boosting). We then propose a pro...
Autores principales: | Booth, David E., Gopalakrishna-Remani, Venugopal, Cooper, Matthew L., Green, Fiona R., Rayman, Margaret P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429712/ https://www.ncbi.nlm.nih.gov/pubmed/34504230 http://dx.doi.org/10.1038/s41598-021-97412-2 |
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