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Reinforcement learning derived chemotherapeutic schedules for robust patient-specific therapy

The in-silico development of a chemotherapeutic dosing schedule for treating cancer relies upon a parameterization of a particular tumour growth model to describe the dynamics of the cancer in response to the dose of the drug. In practice, it is often prohibitively difficult to ensure the validity o...

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Detalles Bibliográficos
Autores principales: Eastman, Brydon, Przedborski, Michelle, Kohandel, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429726/
https://www.ncbi.nlm.nih.gov/pubmed/34504141
http://dx.doi.org/10.1038/s41598-021-97028-6