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Regulation of low-density lipoprotein receptor expression in triple negative breast cancer by EGFR-MAPK signaling

Expression of the low-density lipoprotein receptor (LDLR) has been shown to play a critical role in hypercholesterolemia-associated breast cancer growth and is associated with shorter recurrence-free survival in human breast cancer studies. We sought to identify how circulating LDL cholesterol and t...

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Detalles Bibliográficos
Autores principales: Scully, Tiffany, Kase, Nathan, Gallagher, Emily J., LeRoith, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429745/
https://www.ncbi.nlm.nih.gov/pubmed/34504181
http://dx.doi.org/10.1038/s41598-021-97327-y