Cargando…

DNAM-1/CD226 is functionally expressed on acute myeloid leukemia (AML) cells and is associated with favorable prognosis

DNAM-1 is reportedly expressed on cytotoxic T and NK cells and, upon interaction with its ligands CD112 and CD155, plays an important role in tumor immunosurveillance. It has also been reported to be functionally expressed by myeloid cells, but expression and function on malignant cells of the myelo...

Descripción completa

Detalles Bibliográficos
Autores principales: Chashchina, Anna, Märklin, Melanie, Hinterleitner, Clemens, Salih, Helmut R., Heitmann, Jonas S., Klimovich, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429762/
https://www.ncbi.nlm.nih.gov/pubmed/34504191
http://dx.doi.org/10.1038/s41598-021-97400-6