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Depletion of PD-1 or PD-L1 did not affect the mortality of mice infected with Mycobacterium avium

The programmed cell death-1 (PD-1) and programmed cell death-ligand 1 (PD-L1) pathway could affect antimicrobial immune responses by suppressing T cell activity. Several recent studies demonstrated that blocking of the PD-1/PD-L1 pathway exacerbated Mycobacterium tuberculosis infection. However, the...

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Detalles Bibliográficos
Autores principales: Nakajima, Masayuki, Matsuyama, Masashi, Kawaguchi, Mio, Matsumura, Sosuke, Kiwamoto, Takumi, Matsuno, Yosuke, Morishima, Yuko, Yoshida, Kazufumi, Sherpa, Mingma Thsering, Yazaki, Kai, Tanaka, Ryota, Okiyama, Naoko, Muratani, Masafumi, Ishii, Yukio, Hizawa, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429769/
https://www.ncbi.nlm.nih.gov/pubmed/34504192
http://dx.doi.org/10.1038/s41598-021-97391-4