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A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks

Heterodimeric capping protein (CP/CapZ) is an essential factor for the assembly of branched actin networks, which push against cellular membranes to drive a large variety of cellular processes. Aside from terminating filament growth, CP potentiates the nucleation of actin filaments by the Arp2/3 com...

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Detalles Bibliográficos
Autores principales: Funk, Johanna, Merino, Felipe, Schaks, Matthias, Rottner, Klemens, Raunser, Stefan, Bieling, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429771/
https://www.ncbi.nlm.nih.gov/pubmed/34504078
http://dx.doi.org/10.1038/s41467-021-25682-5