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miR-363-3p inhibits rat lung alveolar type II cell proliferation by downregulating STRA6 expression and induces cell apoptosis via cellular oxidative stress and G1-phase cell cycle arrest

BACKGROUND: miR-363-3p, the retinoid signaling pathway (RSP), and its associated membrane receptor, stimulated by retinoic acid 6 (STRA6), participate in lung development. We hypothesize that miR-363-3p is involved in lung cell proliferation and apoptosis by regulating the expression of STRA6, and t...

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Detalles Bibliográficos
Autores principales: Zheng, Jintao, Zhu, Shibo, Xu, Huiyu, Li, Jiequan, Tang, Huajian, Zhou, Yanfen, Huang, Zhaomei, Liu, Guoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429880/
https://www.ncbi.nlm.nih.gov/pubmed/34584880
http://dx.doi.org/10.21037/tp-21-303