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miR-363-3p inhibits rat lung alveolar type II cell proliferation by downregulating STRA6 expression and induces cell apoptosis via cellular oxidative stress and G1-phase cell cycle arrest
BACKGROUND: miR-363-3p, the retinoid signaling pathway (RSP), and its associated membrane receptor, stimulated by retinoic acid 6 (STRA6), participate in lung development. We hypothesize that miR-363-3p is involved in lung cell proliferation and apoptosis by regulating the expression of STRA6, and t...
Autores principales: | Zheng, Jintao, Zhu, Shibo, Xu, Huiyu, Li, Jiequan, Tang, Huajian, Zhou, Yanfen, Huang, Zhaomei, Liu, Guoqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429880/ https://www.ncbi.nlm.nih.gov/pubmed/34584880 http://dx.doi.org/10.21037/tp-21-303 |
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