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Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Regulate Macrophage Polarization to Attenuate Systemic Lupus Erythematosus-Associated Diffuse Alveolar Hemorrhage in Mice

BACKGROUND AND OBJECTIVES: To investigate the effect and the underlying mechanism of exosomes secreted by human umbilical cord mesenchymal stem cells (hUCMSCs) on diffuse alveolar hemorrhage (DAH) in murine lupus. METHODS AND RESULTS: Exosomes were extracted from cultured hUCMSCs by ultracentrifugat...

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Detalles Bibliográficos
Autores principales:	Chen, Xun, Wei, Qing, Sun, Hongmei, Zhang, Xiaobo, Yang, Changrong, Tao, Ying, Nong, Guangmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Stem Cell Research 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429939/ https://www.ncbi.nlm.nih.gov/pubmed/33906978 http://dx.doi.org/10.15283/ijsc20156

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