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CYP2C19 Genotyping May Provide a Better Treatment Strategy when Administering Escitalopram in Chinese Population

Depression disorder is one of the most serious mental illnesses in the world. Escitalopram is the essential first-line medication for depression disorder. It is the substrate of hepatic cytochrome P450 (CYP) enzyme CYP2C19 with high polymorphism. The effect of CYP2C19 on pharmacokinetics and pharmac...

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Detalles Bibliográficos
Autores principales: Huang, Xinyi, Li, Chao, Li, Chaopeng, Li, Zhenyu, Li, Xiaohui, Liao, Jianwei, Rao, Tai, Chen, Lulu, Gao, Lichen, Ouyang, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429954/
https://www.ncbi.nlm.nih.gov/pubmed/34512354
http://dx.doi.org/10.3389/fphar.2021.730461