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Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis

OBJECTIVE: The nuclear receptor corepressor 1 (NCOR1) and the silencing mediator of retinoic acid and thyroid hormone (SMRT, also known as NCOR2) play critical and specific roles in nuclear receptor action. NCOR1, both in vitro and in vivo specifically regulates thyroid hormone (TH) action in the co...

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Detalles Bibliográficos
Autores principales: Ritter, Megan J., Amano, Izuki, Imai, Norihiro, Soares De Oliveira, Lorraine, Vella, Kristen R., Hollenberg, Anthony N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429965/
https://www.ncbi.nlm.nih.gov/pubmed/34390859
http://dx.doi.org/10.1016/j.molmet.2021.101315