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A familial Danish dementia rat shows impaired presynaptic and postsynaptic glutamatergic transmission
Familial British dementia and familial Danish dementia are neurodegenerative disorders caused by mutations in the gene integral membrane protein 2B (ITM2b) encoding BRI2, which tunes excitatory synaptic transmission at both presynaptic and postsynaptic termini. In addition, BRI2 interacts with and m...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429969/ https://www.ncbi.nlm.nih.gov/pubmed/34416235 http://dx.doi.org/10.1016/j.jbc.2021.101089 |