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A familial Danish dementia rat shows impaired presynaptic and postsynaptic glutamatergic transmission

Familial British dementia and familial Danish dementia are neurodegenerative disorders caused by mutations in the gene integral membrane protein 2B (ITM2b) encoding BRI2, which tunes excitatory synaptic transmission at both presynaptic and postsynaptic termini. In addition, BRI2 interacts with and m...

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Detalles Bibliográficos
Autores principales: Yin, Tao, Yao, Wen, Norris, Kelly A., D’Adamio, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429969/
https://www.ncbi.nlm.nih.gov/pubmed/34416235
http://dx.doi.org/10.1016/j.jbc.2021.101089