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Identification of invariant chain CD74 as a functional receptor of tissue inhibitor of metalloproteinases-1 (TIMP-1)

Multifunctionality of tissue inhibitor of metalloproteinases-1 (TIMP-1) comprising antiproteolytic as well as cytokinic activity has been attributed to its N-terminal and C-terminal domains, respectively. The molecular basis of the emerging proinflammatory cytokinic activity of TIMP-1 is still not c...

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Detalles Bibliográficos
Autores principales: Schoeps, Benjamin, Eckfeld, Celina, Flüter, Laura, Keppler, Selina, Mishra, Ritu, Knolle, Percy, Bayerl, Felix, Böttcher, Jan, Hermann, Chris D., Häußler, Daniel, Krüger, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429975/
https://www.ncbi.nlm.nih.gov/pubmed/34391782
http://dx.doi.org/10.1016/j.jbc.2021.101072