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Phosphorylation of slit diaphragm proteins NEPHRIN and NEPH1 upon binding of HGF promotes podocyte repair

Phosphorylation (activation) and dephosphorylation (deactivation) of the slit diaphragm proteins NEPHRIN and NEPH1 are critical for maintaining the kidney epithelial podocyte actin cytoskeleton and, therefore, proper glomerular filtration. However, the mechanisms underlying these events remain large...

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Detalles Bibliográficos
Autores principales: Solanki, Ashish K., Arif, Ehtesham, Srivastava, Pankaj, Furcht, Christopher M., Rahman, Bushra, Wen, Pei, Singh, Avinash, Holzman, Lawrence B., Fitzgibbon, Wayne R., Budisavljevic, Milos N., Lobo, Glenn P., Kwon, Sang-Ho, Han, Zhe, Lazzara, Matthew J., Lipschutz, Joshua H., Nihalani, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429977/
https://www.ncbi.nlm.nih.gov/pubmed/34391780
http://dx.doi.org/10.1016/j.jbc.2021.101079