Safety, Pharmacokinetics, and Pharmacodynamics of a Single Bolus of the γ-aminobutyric Acid (GABA) Receptor Potentiator HSK3486 in Healthy Chinese Elderly and Non-elderly

Background: The present clinical trial investigated the potential influences of dosage and age on the pharmacokinetic properties and safety profile of HSK3486, and whether any adjustment in dosing regimen is necessary in elderly patients. Methods: Twenty-four elderly participants (65–73 years) were...

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Detalles Bibliográficos
Autores principales: Li, Xiaojiao, Yang, Deming, Li, Qianqian, Wang, Hong, Wang, Meng, Yan, Pangke, Wu, Nan, Li, Fangqiong, Ma, Shiping, Ding, Yanhua, Liu, Jingrui, Wang, Hushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430033/
https://www.ncbi.nlm.nih.gov/pubmed/34512361
http://dx.doi.org/10.3389/fphar.2021.735700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430033/
https://www.ncbi.nlm.nih.gov/pubmed/34512361
http://dx.doi.org/10.3389/fphar.2021.735700

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