PRG5 Knockout Precipitates Late-Onset Hypersusceptibility to Pilocarpine-Induced Juvenile Seizures by Exacerbating Hippocampal Zinc Signaling-Mediated Mitochondrial Damage

INTRODUCTION: Epileptogenesis is understood as the plastic process that produces a persistent reorganization of the brain’s neural network after a precipitating injury (recurrent neonatal seizures, for instance) with a latent period, finally leading to neuronal hyperexcitability. Plasticity-related...

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Detalles Bibliográficos
Autores principales: Wang, Dandan, Jin, Mei-fang, Li, Lili, Liu, Yueying, Sun, Yuxiao, Ni, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430038/
https://www.ncbi.nlm.nih.gov/pubmed/34512249
http://dx.doi.org/10.3389/fnins.2021.715555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430038/
https://www.ncbi.nlm.nih.gov/pubmed/34512249
http://dx.doi.org/10.3389/fnins.2021.715555

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