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The related coactivator complexes SAGA and ATAC control embryonic stem cell self-renewal through acetyltransferase-independent mechanisms

SAGA (Spt-Ada-Gcn5 acetyltransferase) and ATAC (Ada-two-A-containing) are two related coactivator complexes, sharing the same histone acetyltransferase (HAT) subunit. The HAT activities of SAGA and ATAC are required for metazoan development, but the role of these complexes in RNA polymerase II trans...

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Detalles Bibliográficos
Autores principales: Fischer, Veronique, Plassard, Damien, Ye, Tao, Reina-San-Martin, Bernardo, Stierle, Matthieu, Tora, Laszlo, Devys, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430043/
https://www.ncbi.nlm.nih.gov/pubmed/34433046
http://dx.doi.org/10.1016/j.celrep.2021.109598