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Substance P and Alpha-Calcitonin Gene-Related Peptide Differentially Affect Human Osteoarthritic and Healthy Chondrocytes

Osteoarthritis (OA) is a degenerative joint disease that not only causes cartilage loss but also structural damage in all joint tissues. Joints are innervated by alpha-calcitonin gene-related peptide (αCGRP) and substance P (SP)-positive sensory nerve fibers. Alteration of sensory joint innervation...

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Detalles Bibliográficos
Autores principales: Stöckl, Sabine, Eitner, Annett, Bauer, Richard J., König, Matthias, Johnstone, Brian, Grässel, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430215/
https://www.ncbi.nlm.nih.gov/pubmed/34512650
http://dx.doi.org/10.3389/fimmu.2021.722884